Amyotrophic Lateral Sclerosis (ALS): Treatment
Although no treatment slows or halts the progression of ALS, there are a number drugs and therapies available to help manage symptoms and make living with ALS easier.

The medication Riluzole (Rilutek®) is approved for the treatment of ALS. This drug, which decreases the release of glutamate, provides symptomatic relief, helps prevent complications and helps patients achieve optimal function and quality of life.

In the early stages of ALS, physical therapy can improve circulation and help prolong muscle use. Various medications may be prescribed as the disease progresses to help control worsening symptoms:

• Baclofen relieves stiffness in the limbs and throat.
• Nutritional supplements called branched-chain amino acids (BCAAs) can help slow muscle decline and weight loss.
• Phenytoin may ease cramps.
• Tricyclic antidepressants can help control excess saliva production.

Other therapies, such as occupational therapy and speech therapy, are also used to treat ALS. Because ALS patients require a diet of high-energy foods that are easy to swallow, a nutritionist is usually assigned to their patient care team.